Abstract
Summary
Ouabain in concentrations from 10-3 to 10-6 M inhibits acid secretion by frog gastric mucosas in vitro and at 10-4 M causes tissue Na to rise and K to fall. Increasing K concentration in the medium from 9 to 29 mM largely abolishes the inhibitory effect of 10-4 M ouabain. We conclude that at least some of the inhibitory effect is the result of alteration of intracellular electrolyte pattern.
Get full access to this article
View all access options for this article.