Abstract
Summary
The hydrolysis of the synthetic substrate BAEE (Benzoyl-1-arginine ethyl ester) by proteolytic enzymes present in plasma is increased by heparin and its synthetic analogue, Mepesulfate. This action of heparin and Mepesulfate is not produced by the calcium binding anticoagulant, potassium oxalate. The hydrolysis of BAEE by plasma is also catalyzed by glass contact resulting in values which are higher and statistically different from those obtained when the reaction is carried out in polyethylene tubes. The implications of these results and possible mechanisms for these findings are considered.
Get full access to this article
View all access options for this article.