Abstract
Summary
Renal extractions of arterial glycocyamine and arginine were determined by sampling urine and right renal venous blood in 25 males studied during diuresis because of hypertensive or urologic disease. Both positive and negative extractions of both compounds were observed. The finding of negative extractions is compatible with the capacity for renal synthesis of these compounds shown in vitro in other species. The finding of positive extractions is discussed in terms of utilization of these compounds in local renal metabolism, in addition to previously postulated roles as substrates for extra-renal syntheses.
Get full access to this article
View all access options for this article.