Abstract
Conclusions
1. The acute hemodynamic effects of oral administration of 300 mg of triamterene are reported in a series of 7 normotensive human subjects. 2. Administration of the agent was associated with a decrease in cardiac output, accompanied by a reduction in central venous pressure, insignificantly diminished left ventricular work, and an increase in peripheral vascular resistance. 3. Coronary blood flow was unchanged and myocardial oxygen consumption maintained at the control level whereas calculated cardiac efficiency was reduced.
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