Abstract
Summary
Adrenocortical hormone secretion of patients with spinal cord transection has been studied by determining urinary and plasma 17-hydroxycorticosteroid concentrations before and after ACTH and by measuring diurnal variation in plasma adrenal steroid levels. These values were compared with those obtained from control subjects and no difference in adrenal hormone secretion was evident. Metabolic inactivation of Cortisol was determined by infusing the steroid intravenously and measuring rate of disappearance from plasma. The rate of steroid degradation in cord-sectioned patients was not different from that of controls.
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