Abstract
Summary
A method for synthesis of radioactive heparin of high unit activity and radioactivity has been described using a process of N-desulfation and N-resulfation. Comparison of the biological identity of the radioactive material with commercial heparin has been made. N-resulfated S35 heparin appears to be similar to biosynthetic S35 heparin in both its clearing and anticoagulant activity as well as its ultimate fate and distribution in the body.
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