Abstract
Summary
The presence of only trace quantities of arachidonic acid in the CEFA of gerbil serum is at variance with the hypothesis of a negative correlation between arachidonic acid levels in CEFA and susceptibility to atherosclerosis. Fasting for 18 hours resulted in a 66% increase of arachidonic acid at the expense of linoleic acid in CEFA of the rat, while in the gerbil, CEFA remained unchanged. In both species, palmitoleic and oleic acids were the major acids associated with cholesterol transport. The CEFA pattern in cholesterol-fed animals suggests an incipient essential fatty acid deficiency.
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