Abstract
Summary
Calcium complexes of oxytetracycline were analyzed by the use of the frog heart method with an improved apparatus employing a vertical shutter, photoelectric transducer, bridge circuit, and recording system. This method was readily applicable to complex biologic solutions and produced results comparable to those in the preceding article obtained by spectrophotometry on pure solutions. The log K of the 1:1 calcium oxy-tetracycline complex was 3.04, compared with 3.19 for the 1:1 complex of citric acid and calcium.
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