Abstract
Summary
Potassium ion augments the amount of infectious Coxsackie B2 virus produced from MKC and MTC. Production of infectious Coxsackie B2 virus was reduced 500 to 2,000 times in MKC and MTC by depletion of potassium from their medium. Similar results were not obtained with Coxsackie B3 virus. Potassium was not required for virus attachment, but did stimulate glycolysis of tissue culture cells. Potassium could be replaced in a deficient medium after 12 hours of infection and still obtain maximal yields of infectious virus in MTC.
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