Abstract
Summary
Using desoxyribosenucleic acid (DNA) as an index of mammary gland growth, crude and purified anterior pituitary extracts were tested for mammary gland growth promoting (mammogenic) effectiveness. Acetone dried AP powder and an initial extract of AP were shown to be effective in stimulating production of mammary gland DNA. Initial residue, Mammogen “A” and “C”, shown previously to produce mammary gland growth in mice, were found to be ineffective in rats. Fractions rich in lactogen and growth hormone were found to be minimally effective in stimulating mammary gland lobule-alveolar growth.
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