Abstract
Summary
1. With the aid of an intragastric buffering technic, albumin and γ-globulin were detected in gastric aspirates of human subjects without gastric disease. 2. The range of albumin concentration in these gastric aspirates was 17-451 μg/ml whereas that for γ-globulin was 33-95 μg/ml. Estimates of the corresponding minimum 24-hour outputs for these 2 proteins were 21-690 mg and 33-384 mg respectively. 3. Saliva aspirated concomitantly with gastric contents also contained these plasma proteins, but not invariably. 4. It is unlikely that the gastric juice proteins derived in significant degree from saliva because of (a) the careful continuous removal of saliva by oral aspiration, and (b) presence of significant amounts of plasma proteins in gastric aspirates of individuals whose saliva did not contain detectable amounts of these proteins.
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