Abstract
Summary
In 6 nephrectomized hypophysectomized dogs, the increase in aldosterone and 17-hydroxycorticoid secretion produced by infusion of angiotensin-II into the arterial blood supplying the adrenal gland was greater than the increase produced by infusion of the same dose into the jugular vein. It is concluded that angiotensin-II can stimulate adrenocortical secretion by a direct action on the adrenal gland.
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