Abstract
Summary
Sera from 167 patients with various enterovirus infections were tested against uninactivated CF antigens to ECHO virus types 12 and 19. Four-fold or greater rises in CF antibody titer, unassociated with the presence of neutralizing antibody to these 2 ECHO virus types, were seen in an appreciable proportion of patients infected with ECHO 4, 6, 9 and 11 viruses, possibly indicating antigenic relationships of the viral moieties responsible for production of CF antibodies in man. No evidence was seen of a relationship between ECHO types 12 and 19 and ECHO 5, ECHO 10 (reoviruses) or ECHO 14, nor was there any good evidence of a relationship between these 2 ECHO virus types and the Coxsackie group A, Coxsackie group B or poliovirus types studied.
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