Abstract
Summary
Evidence is presented that epithelial cells of human amnion and kidney are capable of binding heterologous blood group substances in human sera and in animal tissue extracts, thereby displaying altered blood group phenotypes following short exposures to such sera and extracts. The antigen-binding property of such cells disappears following treatment with trypsin, but reappears gradually upon appropriate recultivation of the cells. The property is apparently lacking in fibroblasts, erythrocytes and HeLa cells.
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