Inhibition of Coagulase Reaction of Pathogenic Staphylococci by Heparin in vitro ∗

Abstract

Summary

Heparin has been shown to prolong coagulase clotting time of 30 strains of staphylococci. This finding suggests that coagulase may interact with an “accessory factor” of plasma to produce a substance analogous or identical to thrombin.