Vitamin B 12 Unsaturated Binding Capacity of Sera from Various Animals. ∗

Abstract

Summary

The vitamin. B₁₂ unsaturated binding capacity (UBBC) of sera from various animals ranged from 0.29 mμg/ml for king crab serum to 6956 mμg/ml for chinook salmon serum. Although exceptions occur, the UBBC of sera from animals with nucleated erythrocytes is higher than that of mammalian sera. The binding capacity for Co⁶⁰ - dimethylbenzimidazolyl cobamide cyanide (cyanocobalamin) and Co⁶⁰ dimethylbenzimidazolyl cobamide coenzyme (DMBC) was the same, suggesting that cobalt ligands may not be involved in binding.