Abstract
Summary
Destruction of chimpanzee kidney cells by 2 of 12 acute sera from patients with clinical infectious hepatitis was noted. The cellular effect has been seen in serial passage. The destructive agents, tentatively named SAM-1 and SAM-2, have been shown in fluorescent antibody and neutralization tests to be serologically cross-reactive with convalescent serum derived from clinical infectious hepatitis. The agents are resistant to heat treatment at 56°C for 30 minutes.
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