Abstract
Summary
Eleven cats were subjected to lesions which were thought to correspond to Nauta's preoptic brain transections in rats. Seven of these exhibited a brief period of hyperactivity from the fourth through the seventh postoperative day, whereas 4 showed no change. Seven also declined physically, ceased drinking and eating, and died(2) or approached death before sacrifice. This decline could not be correlated directly with the periods of hyperactivity. There was no persistent alteration in sleep-wakefulness cycles. The only gross effect on serum electrolytes was concentration concomitant with dehydration. Potassium levels fell corresponding to a decrease in intake.
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