Elevation of Proteolytic Activity in the Pancreas of Hypophysectomized Rats by Hormonal Therapy. ∗

Abstract

Summary

Hypophysectomy of the rat failed to reduce consistently the concentration of PA in the pancreas when computed on the basis of wet weight. When related to mg of nitrogen per g of pancreas the amount of PA was increased. Treatment with STC restored body weight, increased pancreatic weight and total PA. Except when insulin was added to the hormonal regimen, PA did not reach the level observed in the nonhypophysectomized controls.