Abstract
Summary
Sprague - Dawley - Rolfsmeyer rats showing full estrous smears were administered 1 mg/day of ovine lactogen containing 15 IU/mg for 5 days. On day 6, one uterine horn was traumatized and 1 μg EB and 1 and 2 mg lactogen (LGH) were administered on days 6 to 9. On day 10, horns of uteri were separated and processed for DNA. EB had no influence on placentoma formation; whereas, both levels of LGH stimulated placentoma in 1/3 of rats with graded reaction as measured by DNA. EB, .5 μg or 1 μg, with 1 mg LGH improved neither % response nor total DNA in comparison with LGH alone. While lactogenic preparation stimulated placentoma formation, reasons are advanced why it is premature to identify luteotropic action with lactogen.
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