Abstract
Summary
Actinophage injected intraperitoneally into inbred Balb mice appeared almost instantaneously in blood, brain, liver, kidney, spleen, lung and testis. Viable virus was isolated from the blood for 2 days following challenge, from lung, liver and kidney for 6 days, and from testis and spleen for more than 10 days. Mice produced neutralizing antibody within 48 hours after antigenic stimulation. Antibody production was elicited by as few as 107 actinophage particles.
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