Abstract
Summary
Agglutination of human erythrocytes by Coxsackie B virus types 1 and 5 is reported. Optimum titers were obtained with a sedimentation temperature of 37†C and the erythrocytes of newborn infants. A hemagglutination–inhibition (HI) procedure employing Coxsackie B virus types 1, 3, and 5 was used to test paired sera from 25 children infected with Coxsackie B virus types 3. 4. and 5. A significant homologous response was detected in every case except one. A few heterologous responses occurred in children with pre–existing HI antibody to one or more of the 3 test antigens.
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