Abstract
Summary
L-thyroxine secretion rates (TSR) averaged 0.94 μg/100 g/day in 34 male and 25 female albino rats. No sex differences were found. TSR determined 2 weeks after ADRX while on 1% NaCl replacement therapy was significantly reduced by 17% in males and 32% in females. TSR determined after 2 weeks of hydrocortisone replacement (150 μg/day) in addition to 1% NaCl was found to return to normal level. Body weight was not affected by treatments. It was suggested that reduced TSR after ADRX may be due, in part, to reduced feed consumption rather than ADRX per se.
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