Abstract
Summary
Growth hormone isolated from 6 different species was compared for its ability to increase width of epiphyseal plate and to stimulate radio-sulfate incorporation by costal cartilage. Human, beef, monkey, and sheep preparations manifested almost identical effects in the 2 assays. Whale and pig hormones appeared to elicit greater effect in the tibia test. Whale growth hormone was observed to have greater duration of activity to stimulate radio-sulfate incorporation than other preparations studied. Short-term radio-sulfate assay appears to be of value for qualitative detection of growth-promoting activity.
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