Abstract
Summary
Non-coenzyme linked a-glycerophosphate dehydrogenase activity has been demonstrated histochemically in juxtaglomerular cells of rats. Menadione, which increased the activity of rat kidney mitochondria 4- to 5-fold in vitro, was required as intermediate electron carrier when a thiazol substituted monotetrazole was used as final H-acceptor in tissue sections. a-Glycerophosphate dehydrogenase activity of juxtaglomerular cells increased both in ischemic kidneys from renal hypertensive rats and in kidneys from adrenal insufficient animals. Decrease in activity of juxtaglomerular cells was noted both in untouched kidneys from animals bearing a unilateral arterial clamp and in the renal cortex of rats overdosed with DOCA on a high sodium diet.
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