Abstract
Summary
Relationship between serum free cholesterol not combined upon incubation and atheroma development has been studied using sera from normal and cholesterol-fed young cockerels. Original free cholesterol uncombined after incubation of serum from normal, mild spontaneous, and severely atherosclerotic birds is 9, 14, and 67 mean mg % respectively. Amounts combined upon incubation show smaller differences (17, 13, and 23 mean mg %) for the 3 series. Corresponding ranges of per cent original free cholesterol not combined are 17 to 45 for normal, 45 to 56 for mild spontaneous, and 57 to 87% for severe cholesterol-induced atherosclerosis. Results of this study indicate that there is a relationship between serum free cholesterol not combined upon incubation and development of atheroma in young cockerels.
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