Abstract
Summary
DNA synthesis and mitosis in liver cells are partially inhibited 24 hours after operation in rats subjected to both partial hepatectomy and bile duct obstruction; at 48 hours regeneration is greater than after partial hepatectomy alone, although not as marked as that seen at 24 hours after partial hepatectomy. Liver cell proliferation occurs 40 to 48 hours after obstruction of the common bile duct, and is presumably the result of histologically inapparent injury to liver cells.
Get full access to this article
View all access options for this article.