Abstract
Summary
Biological decay curves of Na22 excretion showed good correlation with urinary sodium excretion during alteration of sodium excretion by sodium chloride, DCA and hydrochlorothiazide over periods of 3 to 7 days. During these short intervals, biological decay curves of serum radioactivity and serum specific activity were too variable to allow correlation with urinary sodium excretion. Daily total exchangeable sodium shows a progressive rise and cannot be used to reflect acute changes in sodium balance.
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