Abstract
Conclusions
Hematocrit data from incompatible mice joined in parabiosis suggest that a primary and a secondary anemia-polycythemia may develop. The secondary anemia-polycythemia appears related to an immune response, while the primary does not. The two events may counterbalance or intensify each other, depending on the genetic backgrounds of the mice. Because of this multiplicity of factors, the anemia-polycythemia of parabiosis appears unsuitable as an assay of the host response to incompatible tissue.
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