Abstract
Summary
The sera of rabbits which were homografted with skin are shown to be toxic to lymph node cells of the skin donor rabbit. Cytotoxicity was demonstrated upon incubation in vitro for 2 hours at 37°C. Sera of grafted rabbits became toxic after graft breakdown had commenced (11 days), and reached a peak after the rejection (20-30 days). The sera were in all instances more toxic to lymph node cells of the skin donor than to cells of other rabbits.
The authors wish to acknowledge the technical assistance of C. C. Chamberlain and J. D. McClelland.
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