Abstract
Summary
Neonatal guinea pigs, injected with BGG and adjuvant immediately after birth produce circulating antibody, detectable by PCA but not by agar-diffusion tests. Sera collected 7, 9, 11, and 15 days after intramuscular injection gave 7, 80, 94, and 100% positive PCA reactions, respectively. Rate of antibody production during the first week after birth is lower than that of adults. Capacity for humoral antibody formation probably exists at a reduced level in the fetus.
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