Abstract
Summary
At low ionic strength, atabrine inhibition of myofibrillar ATPase activity was potentiated by Mg++. Ca++ counteracted atabrine inhibition in absence but not in presence of Mg++. The assumption of the occurrence of an Mg-atabrine coordination complex as the strong inhibitor is proposed as the best explanation of the experimental results. At high ionic strength, atabrine failed to inhibit Ca++ activated myofibrillar ATPase (myosin ATPase) with or without Mg++ being present.
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