Studies of Mycobacterium tuberculosis H 37 Rv Grown in vivo

Abstract

Summary

It was shown that in vivo grown tubercle bacilli are readily permeable to glucose and oxidize it to an even greater extent than those grown in vitro. It was therefore concluded that the apparent lack of respiratory response to glucose by in vivo grown tubercle bacilli was not due to either permeability factor or to inability of these cells to oxidize exogenous glucose. Possible causes for the apparent lack of respiratory response of LH₃₇Rv cells to glucose are discussed.