Studies of Mycobacterium tuberculosis H 37 Rv Grown in vivo

Abstract

Summary

The presence of an inhibitor of the electron transport system of a number of mycobacteria and of lung homogenates of normal mice was found in normal mice and in those infected with M. tuberculosis H₃₇Rv. This inhibitor was previously found in tubercle bacilli grown in vivo and in lung extracts from infected mice. This work shows that the amount of inhibitor is greatly increased in animals infected with H₃₇Rv. The significance of these findings is discussed.