Abstract
Summary
Methyl prednisolone and fluorometholone prevented the appearance of CxRP in rabbit serum following subcutaneous injection of mineral oil-Aquaphor emulsion. Fluorometholone was unable to block CxRP responses to 250 r whole body irradiation or to intravenous injection of Thorotrast or Varidase. It did block CxRP responses to intravenous injection of post irradiation seromucoid or TMV and the intravascular formation of antigen-antibody complexes. Under appropriate time dose conditions fluorometholone inhibited both antibody production and CxRP appearance while under other time dose conditions CxRP appearance was prevented without alteration of antibody production.
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