Changes in Liver Tyrosine-α-Ketoglutarate Transaminase Activity During Growth of Walker Carcinosarcoma 256

Abstract

Summary

Liver tyrosine-α-ketoglutarate transaminase activity was not affected by Walker carcinosarcoma 256 in the early stages of tumor growth. During latter stages of tumor growth a 2-fold increase in liver tyrosine transaminase activity was noted. No change was observed in tyrosine transaminase activity in regenerating liver; therefore, it seemed unlikely that increased transaminase activity in the late stages of tumor growth resulted from an enhanced liver mitotic activity.