Abstract
Summary
This report deals with the absence of correlation of acidity and volumerats of flow of gastric secretion from fully vagal (Hollander-Jemerin) and completely vagotomized (Heidenhain) stomach pouches. Variations in rate of secretion were induced by the inhibitory action of a single intravenous dose of insulin (both types of pouch) or of glucagon (vagal pouch only) on flow of juice induced by stimulation with histamine in repeated 10-minute subcutaneous doses. In both types of experiment it was possible to demonstrate a good degree of constancy of acidity in spite of considerable variations in volume-rate. This brings to 6 the number of experimental situations in which such constancy has been observed.
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