Effects of Intra-Adrenal Infusion of Potassium on Urinary Potassium Excretion in the Dog. ∗

Abstract

Summary

1) A technic has been described whereby the dog adrenal may be infused in situ without disturbing its arterial blood supply. 2) Utilizing this technic, infusion into left adrenal arteries of a solution containing high concentrations of potassium did not affect serum potassium concentration or urinary potassium excretion any differently than infusion of similar solution into a non-adrenal artery. It is concluded that the kaliuretic response to potassium infusions is not mediated by a direct action of potassium on the adrenal cortex.