Abstract
Summary
When glycine-1-C14 is injected into rats bearing Ivalon sponges implanted 2 weeks previously, significant radioactivity is found in the various protein fractions (including collagen) of the sponge connective tissue after 6 hours. Adrenalectomy at the time of implantation exerted some influence upon the extent of incorporation into some of the fractions, but administration of hydrocortisone for 2 days to either intact or adrenalectomized animals had no effect. When studies of glycine uptake by sponge-biopsy connective tissue proteins were made in rats of various ages, a steady decrease in rate of incorporation into all fractions was observed as age of the host increased from one month to one year.
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