Abstract
Summary
Serotonin, but not reserpine or lysergic acid (LSD), when given intraperitoneally to rats, decreased uterine (smooth muscle) glycogen levels and phosphorylase activity. Serotonin rapidly decreased glycogen concentration in the diaphragm, rapidly elevated glycogen in heart muscle and in neither instance altered phosphorylase activity. Thus it is possible to produce acute changes in glycogen stores in some tissues without evoking alterations in phosphorylase activity.
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