Abstract
Summary
The mouse diaphragm technic has been adapted to measure insulin-like activity of dialyzed serum. Compared to the response effected by insulin in KRB buffer medium alone, normal rabbit serum inhibited while beef serum albumin enhanced insulin response. Mean serum insulin level of adult rats was significantly greater than rabbits, mice, and dogs and much higher than humans. A significant elevation in serum insulin activity which persisted up to 45 minutes following injection, was found in rabbits injected intravenously with 1 unit/kg insulin.
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