Abstract
Summary
1) The effects of a single dose of DL-Serine on lipide phosphorylation in kidney were studied in the rat.
2) A statistically significant decrease occurred in phospholipide phosphorus of the necrotic kidney as compared to controls. However, there was a 3-fold increase in lipide phosphorylation as shown in the relative specific activities values. 3) A statistically significant increase occurred in % of total lipide phosphorus in phosphatidylethanolamine-serine and phosphatidyl-inositol fraction, in the necrotic kidney as compared to controls. However, a decrease occurred in the lecithin fraction. This increase in lipide phosphorylation in the necrotic kidney apparently involved only the phosphatidylethanolamine-serine and sphingomyelin fractions.
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