Response of Mouse Breast Tumors to L-Triiodothyronine and Irradiation

Abstract

Conclusions

1. Growth rate of transplanted mammary tumor in ZxC57 black F₁ hybrid mice treated with L-triiodothyronine was increased.

2. Average life span of tumor-bearing mice receiving L-triiodothyronine was significantly shortened.

3. In mice receiving L-triiodothyronine and x-ray, increased skin reaction was noted.

4. There was no significant difference between average life span of tumor-bearing groups receiving combined irradiation plus triiodothyronine and the group which received local irradiation only.