Abstract
Summary
1) CF-1 female mice were exposed to approximately 15 a day radiation for 9-15 weeks and challenged at intervals by intraperitoneal inoculation with graded doses of Pseudomonas aeruginosa. Comparison of LD50 of irradiated and control mice in each challenge showed that between 9th and 15th weeks a slight but demonstrable increase in susceptibility to experimental infection had occurred.
2) The increase caused by accumulation of 1350 r during 15 weeks exposure was, however, very much less than that resulting from a single acute exposure to 300 r X-radiation.
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