Abstract
Summary
Changes in organ weights and leucocytes following daily exposure to emotionally disturbing shuttle box or confinement stress were consistently observed. Adrenal hypertrophy and drops in circulating leucocytes were relatively rapid with significant changes observed following 3 to 7 days of stress. Involution of thymus and spleen occurred more slowly, with differences becoming maximum following 14 to 28 days of stress. Differences between experimental and control values returned to non-significant levels in 21 days following termination of stress.
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