Abstract
Summary
1. A cholesterol-induced hyperlipemia was fully counteracted (reduced to normal levels) by feeding beta-sitosterol.
2. The decreased plasma clotting times associated with a hyperlipemia returned to control values when a normal lipid level was attained.
3. An inverse relationship was demonstrated between plasma clotting time in presence of Russell's viper venom and degree of lipemia; i.e., a hyperlipemia resulted in decreased plasma clotting time, and vice versa. 4. Addition of 4% beta-sitosterol to the diet prevented or reversed an increased lipid and cholesterol concentration in liver and aorta.
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