Abstract
Summary
Method is described for inducing atherosclerosis in cockerels by feeding chick growing mash containing .5% commercial cholesterol. Procedures for inducing atherosclerosis in birds by exogenous estrogen have been published(4). Experimental procedures are presented also for studying atherosclerosis induced in cockerels by combining estrogen and cholesterol treatment. Comparison of artery and blood serum changes associated with this disease as induced by these methods shows that a critical level of estrogen causes more rapid plaque formation than cholesterol, and that degree of hypercholesterolemia does not determine extent of atheromatosis.
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