Abstract
Summary
(1) The differential movement of Ca43 and Sr83 across surviving intestinal segments of the rat was studied. (2) In the duodenal segment, Ca43 but not Sr85 was transported against a concentration gradient from mucosa to serosa. (3) In the ileal segment, Sr83 but not Ca45 was transferred against a concentration gradient from serosa to mucosa. (4) Incubation of segments at 0°C, under N2, or in presence of metabolic inhibitors eliminated“active”transport and eliminated strontium-calcium discrimination. (5) Ca-Sr discrimination under given conditions was dependent upon a metabolically active membrane.
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