Abstract
Summary
Concentrations of total ketosteroids, 17-ketosteroids, 17-ketogenic steroids, and dehydroepiandrosterone were determined in urine collected from healthy young men who ingested various quantities of fluid. Individual coefficients of correlation between urine and ketosteroid output varied from significantly positive to negative, with the majority showing no correlation. These results suggest that in most men daily variations in urine volume do not influence excretion of ketosteroids. However, group coefficients of correlation reveal that a significant positive correlation was obtained only for 17-ketosteroids. These data suggest that 1) men who normally produce relatively large volumes of urine also excrete large quantities of this steroid, and 2) type and number of subjects must be considered when calculating group coefficients of correlation.
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