Abstract
Summary
Distributions of enzymatic activities of lactic dehydrogenase and malic dehydrogenase have been studied in human brain. Their activities are increased in gray matter as compared to white matter. There are areas where concentrations of these enzymes seem consistently elevated, with higher concentration of lactic dehydrogenase in caudate nuclei, as compared to other gray matter, and optic nerve as compared to other white matter. In some areas lactic dehydrogenase activity shows no correlation with malic dehydrogenase activity. The significance of these variations is not as yet apparent.
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